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- Antibody Data
- Antigen structure
- References [3]
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- ELISA [1]
- Other assay [2]
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- Product number
- GAU 013-16-02 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- Complement C3a Monoclonal Antibody (K13/16-5.7)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- GAU 013-16-02 detects Complement Componet C3a/C3a (desArg) in human samples. This antibody does not cross-react with C4a or C5a. GAU 013-16-02 has been successfully used in ELISA and Western blot procedures. GAU 013-16-02 can be used as a capture antibody in sandwich ELISA with GAU 017-01-02 as detection antibody. This antibody detects an epitope that is present on human C3, C3a, and C3a (desArg), but does not cross react with C4a or C5a. NOTE: Concentration is lot-dependent and can vary from 0.85-1.15 mg/mL
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- K13/16-5.7
- Vial size
- 400 µL
- Concentration
- 1.00 mg/mL
- Storage
- 4° C, store in dark
Submitted references Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells.
TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells.
Peanuts can contribute to anaphylactic shock by activating complement.
Sartain SE, Turner NA, Moake JL
The Journal of biological chemistry 2018 May 11;293(19):7195-7208
The Journal of biological chemistry 2018 May 11;293(19):7195-7208
TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells.
Sartain SE, Turner NA, Moake JL
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 15;196(2):832-45
Journal of immunology (Baltimore, Md. : 1950) 2016 Jan 15;196(2):832-45
Peanuts can contribute to anaphylactic shock by activating complement.
Khodoun M, Strait R, Orekov T, Hogan S, Karasuyama H, Herbert DR, Köhl J, Finkelman FD
The Journal of allergy and clinical immunology 2009 Feb;123(2):342-51
The Journal of allergy and clinical immunology 2009 Feb;123(2):342-51
No comments: Submit comment
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Sandwich ELISA of C3a/C3a (desArg) using GAU 013-16 as the capture antibody and GAU 017-01B as the biotinylated detection antibody.
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- NULL
